上肢淋巴水肿和持续性疼痛是乳腺癌手术治疗后常见的后遗症。本文旨在分析乳腺癌患者的上肢体积、压痛阈值、神经活动范围、疼痛强度、运动恐惧症、疼痛过度警觉性和灾难性症状。乳腺癌手术后有或没有淋巴水肿的患者。其次，我们旨在调查上肢体积与这些变量之间的关联。描述性观察研究。格拉纳达大学健康科学学院。58 名术后乳腺癌幸存者，其中 29 人患有上肢淋巴水肿，29 人没有上肢淋巴水肿。我们测量了上肢体积（视野法）。此外，还使用数字痛觉计、神经运动范围（桡神经、尺神经和正中神经的神经动力学测试）、疼痛强度（视觉模拟量表）、运动恐惧症、疼痛过度警觉性和灾难化（经过验证的测试）来评估压痛阈值。为了检测测量变量组之间的差异，我们进行了独立样本分析的 t 检验。调整年龄和体重指数后进行简单线性回归分析，以检查淋巴水肿组上肢体积与疼痛变量之间的关联。分析显示，淋巴水肿组双侧咬肌压力痛阈较低（起点 P≤ 0.036；插入P≤0.046），颞肌（插入P≤0.021），枕下肌（P≤0.036）；第二肋骨（P≤0.014）、第三肋骨（P≤0.001）和第十肋骨（P≤0.001）；颞肌受影响侧（原点 P=0.025）；颞下颌关节（P=0.024）；患侧正中神经（P=0.047）、尺神经（P=0.042）和健侧桡神经（P=0.039）的神经活动范围；和更大的运动恐惧症（P=0.042）。线性回归分析仅显示淋巴水肿组上肢体积与桡神经神经活动范围之间存在显着相关性（P=0.020）。其余变量未获得显着关联。这些发现表明，淋巴水肿的存在可能会导致该人群普遍机械敏感性和对运动的恐惧水平升高。上肢淋巴水肿可导致该人群机械敏感性和运动相关恐惧的升高。乳腺癌幸存者。因此，快速康复方法应重点关注筛查和康复方法，以发现和控制这种后遗症。

Lymphedema of the upper limbs and persistent pain are frequent sequelae after surgical treatment of breast cancer.The aim of this paper was to analyze the upper limb volume, pressure pain threshold, neural range of motion, pain intensity, kinesiophobia, pain hypervigilance and catastrophizing in patients with and without lymphoedema after breast cancer surgery. Secondly, we aimed to investigated the association between upper limb volume and these variables.Descriptive observational study.Faculty of Health Sciences of the University of Granada.Fifty-eight post-surgical breast cancer survivors, 29 with upper limb lymphoedema and 29 without lymphoedema.We measured upper limb volume (perimetric method). Also, pressure pain thresholds were assessed with a digital algometer, neural range of motion (neurodynamic test for radial, ulnar and median nerves), pain intensity (visual analogue scale), kinesiophobia, pain hypervigilance and catastrophizing (validated tests). To detect differences between the groups for the measurement variables we performed a t-test for independent samples analysis. A simple linear regression analysis adjusting for age and body mass index was performed to check the association among upper limb volume and pain variables in the group with lymphoedema.The analysis showed that lymphoedema group had lower pressure pain threshold bilaterally in the masseter (origin P≤0.036; insertion P≤0.046), temporalis (insertion P≤0.021), suboccipitalis (P≤0.036); second (P≤0.014), third (P≤0.001) and tenth rib (P≤0.001); affected side of the temporalis (origin P=0.025); temporomandibular joint (P=0.024); neural range of motion in the median nerve (P=0.047), ulnar (P=0.042) on the affected side and radial (P=0.039) on the unaffected side; and greater kinesiophobia (P=0.042). Linear regression analysis only showed a significant association between upper limb volume and neural range of motion in the radial nerve (P=0.020) in the lymphedema group. No significant associations were obtained for the rest of variables.These findings suggest that the presence of lymphoedema may contribute to an increased level of generalized mechanosensitivity and fear to movement in this population.Upper limb lymphedema can lead to heightened mechanosensitivity and movement-related fear in breast cancer survivors. Therefore, fast track rehabilitation approach should be focus in screening and rehabilitation methods for detection and control this sequalae.