研究动态
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单孔机器人辅助简单前列腺切除术后偶发前列腺癌:多机构报告 (SPARC)。

Incidental prostate carcinoma after single-port robot-assisted simple prostatectomy: a multi-institutional report (SPARC).

发表日期:2024 Oct
作者: Roxana Ramos-Carpinteyro, Nicolas Soputro, Adriana M Pedraza, Ruben S Calvo, Michael Raver, Celeste Manfredi, Yuzhi Wang, Jaya S Chavali, Kennedy Okhawere, Carter Mikesell, Ethan Ferguson, Michael Stifelman, Ketan K Badani, Riccardo Autorino, Craig Rogers, Mutahar Ahmed, Zeyad R Schwen, Simone Crivellaro, Jihad Kaouk
来源: Minerva Urology and Nephrology

摘要:

单孔机器人辅助单纯前列腺切除术是一种微创替代方案,适用于症状严重和/或药物治疗失败的大面积良性前列腺增生患者。最近的文献显示,单纯前列腺切除术后偶发前列腺癌的发生率为 1.8% 至 13.0%。我们的目标是报告单端口机器人辅助简单前列腺切除术后偶发前列腺癌的发生率,并将我们的研究结果与其他方法进行比较。单端口高级研究联盟 [SPARC] 对所有初始连续单端口前列腺切除术的多机构回顾性分析2019 年至 2023 年,来自 6 个中心的 11 名外科医生进行了端口机器人辅助的简单前列腺切除术病例。我们的主要结果是腺瘤标本中偶发前列腺癌的发生率。我们使用描述性统计来分析数据。在没有转换或额外端口的情况下,总共成功执行了 235 个案例。病理分析发现11名患者(4.6%)偶发前列腺癌。肿瘤累及的组织的中位百分比为5%。有临床意义的前列腺癌的总体发生率为 2.1%。大多数病例属于格里森 1 级 (55%)。等级组≤3的患者随后接受主动监测,中位随访时间为17个月。一名 Gleason 4 级患者接受了简单的多端口机器人辅助根治性前列腺切除术,获得了满意的功能和肿瘤学结果。单端口机器人辅助简单前列腺切除术的初步多机构经验显示,偶发前列腺癌率为 4.6%,可比MP、腹腔镜和开放技术。
Single-port robot-assisted simple prostatectomy is a minimally invasive alternative for patients with large benign prostatic hyperplasia with severe symptoms and/or failure of medical treatment. In recent literature, the rate of incidental prostate cancer after simple prostatectomy ranges from 1.8% to 13.0%. Our objective is to report the rate of incidental prostate cancer after single-port robot-assisted simple prostatectomy and to compare our findings to other approaches.A Single-Port Advanced Research Consortium [SPARC] multi-institutional retrospective analysis of all initial consecutive single-port robot-assisted simple prostatectomy cases performed from 2019 to 2023 by eleven surgeons from six centers. Our primary outcome was the rate of incidental prostate cancer in adenoma specimens. We used descriptive statistics to analyze the data.A total of 235 cases were performed successfully without conversions or additional ports. Eleven patients (4.6%) were found to have incidental prostate cancer on pathological analysis. The median percentage of tissue involved by the tumor was 5%. The overall rate of clinically significant prostate cancer was 2.1%. Most cases were Gleason Grade Group 1 (55%). Those with Grade Group ≤3 were subsequently managed with active surveillance with a median follow-up of 17 months. A patient with Gleason Grade Group 4 underwent an uncomplicated multi-port robot-assisted radical prostatectomy with satisfactory functional and oncological outcomes.Initial multi-institutional experience with single-port robot-assisted simple prostatectomy showed an incidental prostate cancer rate of 4.6%, comparable to MP, laparoscopic, and open techniques.