现代癌症疗法极大地改善了早期和晚期乳腺癌患者的临床结果。然而，这些进展引起了人们对潜在的短期和长期毒性（包括心血管毒性）的担忧。因此，了解导致心血管毒性的常见危险因素和潜在病理生理机制对于确保最佳乳腺癌结果至关重要。虽然心脏肿瘤学已成为应对这些挑战的子专业，但所有心脏病专家都必须认识并理解癌症治疗对心血管的影响。本综述旨在全面概述与现代乳腺癌治疗相关的潜在心血管不良影响。提出了一种预防、诊断和治疗工作流程，以尽量减少心血管毒性对患者结果的影响。该工作流程的关键方面包括定期监测心血管功能、早期检测和管理与癌症治疗相关的心血管毒性以及优化心血管危险因素控制。通过强调某些领域的知识差距，本综述旨在强调心脏肿瘤学研究在确保乳腺癌患者整体健康方面的关键作用。© 作者 2024。由牛津大学出版社出版代表欧洲心脏病学会。版权所有。如需商业重复使用，请联系 reprints@oup.com 获取转载和转载的翻译权。所有其他权限都可以通过我们网站文章页面上的权限链接通过我们的 RightsLink 服务获得 - 如需了解更多信息，请联系journals.permissions@oup.com。

Modern cancer therapies greatly improve clinical outcomes for both early and advanced breast cancer patients. However, these advances have raised concerns about potential short- and long-term toxicities, including cardiovascular toxicities. Therefore, understanding the common risk factors and underlying pathophysiological mechanisms contributing to cardiovascular toxicity is essential to ensure best breast cancer outcomes. While cardio-oncology has emerged as a sub-speciality to address these challenges, it is essential that all cardiologists recognize and understand the cardiovascular consequences of cancer therapy. This review aims to provide a comprehensive overview of the potential adverse cardiovascular effects associated with modern breast cancer therapies. A preventive, diagnostic, and therapeutic workflow to minimize the impact of cardiovascular toxicity on patient outcomes is presented. Key aspects of this workflow include regular monitoring of cardiovascular function, early detection and management of cancer therapy-related cardiovascular toxicities, and optimization of cardiovascular risk factor control. By highlighting the gaps in knowledge in some areas, this review aims to emphasize the critical role of cardio-oncology research in ensuring the holistic well-being of patients with breast cancer.© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.