MANTIS 闭合装置（MCD：波士顿科学公司，美国）是一种带有锋利爪的可重新打开的夹子，是在内窥镜粘膜下剥离术 (ESD) 后使用的闭合装置。我们的目的是评估结直肠 ESD 后 MCD 快速、完全闭合的有效性。对 2023 年 4 月至 2024 年 1 月期间 ESD 后 20-60 mm 结直肠病灶采用 MCD 闭合的病例进行了回顾。主要终点是通过 MCD 完全闭合 ESD 缺陷。次要终点包括闭合时间、延迟出血 (DB)、穿孔 (DP) 和 ESD 后凝血综合征 (PECS)。 MCD 的使用方法包括 1. 抓住缺损周围的肛门侧粘膜，2. 将其推向缺损周围的口腔侧粘膜并展开，3. 添加几个可重新打开的夹子（Sure Clip、Micro-Tech、中国）完全关闭。对 61 例 MCD 病例进行了分析。平均肿瘤大小为32.3±9.2毫米。完全闭合率为98.4%，闭合时间（平均值±标准差：SD）为6.9±2.6分钟。 MCD和Sure夹的数量（平均值±SD）分别为1.0±0.1和4.7±1.4。 DP/DB/PECS 率分别为 0%、0% 和 9.8%。使用 MCD.Thieme 成功实现结直肠 ESD 后的快速完全闭合。版权所有。

The MANTIS Closure Device (MCD: Boston Scientific, USA), a reopenable clip with a sharp claw, is a closure device used after endoscopic submucosal dissection (ESD). We aimed to evaluate the effectiveness of MCD for fast and complete closure after colorectal ESD.Cases that underwent closure with MCD after ESD of colorectal lesions 20-60 mm between April 2023 and January 2024 were reviewed. The primary endpoint was the complete closure of the ESD defect with MCD. Secondary endpoints included closure time, delayed bleeding (DB), perforation (DP), and post-ESD coagulation syndrome (PECS). The usage of MCD involved 1. grasping the anal-side mucosa around the defect, 2. pushing it toward the oral-side mucosa around the defect and deploying it, 3. adding several re-openable clips (Sure clip, Micro-Tech, China) for complete closure.Sixty-one cases with MCD were analyzed. The mean tumor size was 32.3±9.2 mm. The complete closure rate was 98.4% and closure time (mean±standard deviation: SD) was 6.9±2.6 mins. The number of MCD and Sure clip (mean±SD) were 1.0±0.1 and 4.7±1.4. The rates of DP/DB/PECS were 0%, 0%, and 9.8%, respectively.Fast and complete closure after colorectal ESD was successfully achieved using MCD.Thieme. All rights reserved.