通过医疗或手术追求与其性别认同一致的跨性别者面临着家庭建设的挑战，因为医学界缺乏满足跨性别或非二元性别人士生殖需求的理解或基础设施。生育力保留（FP）为跨性别群体提供了一个重要的机会，使个人能够对其生殖选择行使自主权。虽然生育力保存已在癌症患者等其他人群中得到广泛研究，但跨性别和性别非二元多样化 (TGD) 个体独特的生物学和临床护理对直接转化为顺性别个体提供的服务提出了挑战。此外，据报道，尽管跨性别者普遍希望生育孩子，但跨性别社区的计划生育服务并未得到充分利用。本综述旨在提供有关 TGD 个体可用的当前护理标准和实验性 FP 选项及其潜在生殖结果的最新信息。我们还将从生物学/医学方面和 TGD 人群的角度讨论 FP 成功利用的障碍。通过认识到 TGD 人群面临的独特的家庭建设挑战和潜在的改进领域，可以做出适当的调整，以更好地支持 TGD 社区的生育力保存。

Transgender individuals who pursue alignment with their gender identity, through medical treatments or surgery face challenges to family building because the medical community lacks the understanding or infrastructure to serve the reproductive needs of transgender or non-binary people. Fertility preservation (FP) offers a crucial opportunity for the transgender community, enabling individuals to exercise autonomy over their reproductive choices. While fertility preservation has been extensively studied in other populations such as cancer patients, the unique biology and clinical care of the transgender and gender non-binarydiverse (TGD) individuals has challenged direct translation of what can be offered for cisgender individuals. Additionally, the FP services in transgender communities are reportedly under-utilized, despite the prevalent desire of TGD individuals to have children. This review aims to provide up-to-date information on the current standard of care and experimental FP options available to TGD individuals and their potential reproductive outcomes. We will also discuss the barriers to the success of FP utilization, from both the biology/medical aspect and the perspectives of TGD population. By recognizing the unique family building challenges faced by TGD people and potential areas of improvement, appropriate adjustments can be made to better support fertility preservation in the TGD community.