让我们开始发挥作用：药物敏感性分析以实现精准肉瘤医学。
Let's get functional: Drug sensitivity profiling to enable precision sarcoma medicine.
发表日期：2024 Oct 03
作者：
Claudia R Ball, Stefan Fröhling
来源：
Cell Stem Cell
摘要：
患者来源的肿瘤模型中的药物敏感性分析为改善缺乏有效疗法的癌症的结果提供了新的希望。 Al Shihabi 等人1 证明，骨和软组织肉瘤的短期培养物能够对多种药物和组合进行具有临床意义的筛选，标志着这些高风险疾病的个性化护理取得了重大进展。版权所有 © 2024 Elsevier Inc.。预订的。
Drug sensitivity profiling in patient-derived tumor models offers new hope for improving outcomes in cancers lacking effective therapies. Al Shihabi et al.1 demonstrate that short-term cultures from bone and soft tissue sarcomas enable clinically meaningful screening of multiple drugs and combinations, marking a significant advance in personalized care for these high-risk diseases.Copyright © 2024 Elsevier Inc. All rights reserved.