研究动态
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当提交多个息肉进行肠癌筛查计划时,需要对多少个息肉进行组织学评估?

How many polyps need to be histologically assessed when multiple polyps are submitted for the Bowel Cancer Screening Program?

发表日期:2024 Oct 07
作者: Newton A C S Wong, Hannah E Jones, Katherine M Halloran
来源: HISTOPATHOLOGY

摘要:

自 2020 年以来,接受英国肠癌筛查计划 (BCSP) 的患者切除的息肉数量有所增加。在英国,一般细胞病理学的工作量也继续不成比例地增加,超过了顾问病理学家的数量。针对 BCSP 患者的光学诊断计划尚未、也可能不会在英格兰的每家医院实施。因此,以下研究旨在确定是否仅需要对一定数量的切除息肉进行组织学评估,以一致地指导 BCSP 患者的息肉切除术后管理,以及是否可以丢弃超出该数量的所有剩余较小息肉。这项回顾性研究考虑了所有2016 年至 2024 年提交给一家大型英语教学医院细胞病理学部门的 BCSP 标本/病例。只有切除了 6 个或更多息肉且内窥镜报告注明个体大小的病例才纳入最终研究队列。在 8066 例中向上述科室提交的 BCSP 病例中,345 例中有 6 个或以上息肉。对 135 例病例的最终研究队列的分析表明,根据 2020 年英国胃肠病学会息肉切除术后指南,对内窥镜测量的七个最大息肉的评估足以正确指导 BCSP 患者的后续管理。如果患者需要切除多个息肉,则只需对七个最大的息肉进行组织学评估,其余较小的息肉可以丢弃,不会影响患者的 BCSP 相关管理。© 2024 John Wiley
Since 2020 there has been an increase in the number of polyps removed from patients scoped for the Bowel Cancer Screening Programme (BCSP) of England. General cellular pathology workload also continues to increase disproportionately ahead of consultant pathologist numbers in the United Kingdom. The Optical Diagnosis initiative for BCSP patients has not yet, and may not be, implemented at every hospital in England. The following study therefore aimed to determine whether only a certain number of removed polyps need to be histologically assessed to consistently guide a BCSP patient's post-polypectomy management, and whether all remaining smaller polyps beyond that number could then be discarded.This retrospective study considered all BCSP specimens/cases submitted to the Cellular Pathology department of a large English teaching hospital from 2016 to 2024. Only cases with six or more resected polyps, for which the endoscopic report stated individual sizes, were included in the final study cohort.Of the 8066 BCSP cases submitted to the aforementioned department, there were six or more polyps for 345 cases. Analysis of the final study cohort of 135 cases showed that assessment of the seven largest polyps measured endoscopically was sufficient to correctly guide follow-up management of the BCSP patient as per the 2020 British Society of Gastroenterology post-polypectomy guidelines.When colonoscopy of a BCSP patient leads to removal of multiple polyps, only the seven largest polyps need to be assessed histologically and the remaining smaller polyps could be discarded with no impact to the patient's BCSP-related management.© 2024 John Wiley & Sons Ltd.