虽然乳腺癌的立即乳房重建率正在上升，但在 65 岁以上的女性中，这种率仍然很低。目的是调查接受基于植入物的即刻乳房重建的 65 岁以上女性的手术结果。基于人群的斯德哥尔摩乳房重建数据库包括 2005 年在瑞典斯德哥尔摩接受基于植入物的即刻乳房重建的所有患有乳腺癌的成年女性-2015年。立即乳房重建后 30 天内的主要结果是：需要抗生素的感染和再次手术。植入物移除是次要结果。将 65 岁以上的女性与年轻年龄组进行比较。主要结局采用卡方检验和多变量logistic回归，次要结局采用Kaplan-Meier分析。1749例即刻乳房再造病例中，140例（8.0%）为65岁以上女性。中位随访时间为 74 个月 (1-198)。 65 岁以上女性（140 名女性中有 22 名，15.7%）术后感染并不比 65 岁以下女性（1609 名女性中有 303 名，18.8%；P = 0.221）更常见。 65岁以上女性的再次手术频率高于其他年龄组（65岁以上：8.6%；50-64岁：6.5%；40-49岁：3.5%；40岁以下：1.6%；P < 0.001），然而，在多变量分析中，年龄超过 65 岁并不是独立危险因素（OR 1.00，95% c.i. 0.44 至 2.28）。总体而言，6 年种植体移除概率为 11.4%（8.1% 由于并发症，3.3% 由于患者偏好）。无论出于哪种原因，年龄组之间均无统计学显着差异（分别为 P = 0.085 和 P = 0.794）。相比之下，在精心挑选的 65 岁以上患者中，年龄较大与基于植入物的即刻乳房重建术后较差的手术结果无关。与他们的年轻同行。© 作者 2024。由牛津大学出版社代表 BJS Foundation Ltd 出版。

While immediate breast reconstruction rates in breast cancer are increasing, they remain low in women over 65 years old. The aim was to investigate surgical outcomes in women older than 65 years receiving implant-based immediate breast reconstruction.The population-based Stockholm Breast Reconstruction Database includes all adult women with breast cancer receiving an implant-based immediate breast reconstruction in Stockholm, Sweden, 2005-2015. Primary outcomes within 30 days from immediate breast reconstruction were: infection requiring antibiotics and reoperation on. Implant removal was a secondary outcome. Women more than 65 years were compared with younger age groups. Chi-square tests and multivariable logistic regression were applied for the primary outcomes, and Kaplan-Meier analysis for the secondary outcome.Among 1749 cases of immediate breast reconstruction, 140 (8.0%) were in women more than 65 years. Median follow-up was 74 months (1-198). Postoperative infection was not more common in women older than 65 years old (22 of 140, 15.7%) than in women under 65 years old (303 of 1609, 18.8%; P = 0.221). Reoperation on was more frequent in women older than 65 years than in other age groups (more than 65: 8.6%; 50-64: 6.5%; 40-49: 3.5%; less than 40: 1.6%; P < 0.001), however, age older than 65 years was not an independent risk factor in the multivariable analysis (OR 1.00, 95% c.i. 0.44 to 2.28). Overall, 6-year probability of implant removal was 11.4%, (8.1% due to complications and 3.3% due to patient preference). There was no statistically significant difference between age groups for either reason (P = 0.085 and P = 0.794 respectively).Older age alone was not associated with worse surgical outcomes after implant-based immediate breast reconstruction in highly selected patients older than 65 years when compared with their younger counterparts.© The Author(s) 2024. Published by Oxford University Press on behalf of BJS Foundation Ltd.