一名 54 岁男性因左下腹疼痛就诊。 CT 检查没有发现他疼痛的原因，但发现胰尾有一个 2.0 厘米的偶然增强病变。在 MRI 上，该病变过度增强且扩散受限，怀疑为神经内分泌肿瘤。然而，超声内镜引导下的活检仅产生良性胰腺组织。由于这种不一致，进行了 64 Cu-DOTATATE PET/CT。胰尾病变充满示踪剂，表明分化良好的神经内分泌肿瘤。根据 PET 检查结果，患者接受了远端胰腺切除术。手术病理学仅显示伴有胰岛聚集的局灶性慢性胰腺炎，这是之前在 DOTATATE PET/CT 上未描述的神经内分泌肿瘤的模拟物。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

A 54-year-old man presented with left lower quadrant pain. CT showed no cause for his pain but identified an incidental 2.0-cm enhancing lesion in the pancreatic tail. On MRI, this lesion was hyperenhancing and diffusion-restricting, suspicious for a neuroendocrine tumor. However, EUS-guided biopsy yielded only benign pancreatic tissue. Due to this discordance, 64 Cu-DOTATATE PET/CT was performed. The pancreatic tail lesion was tracer-avid, suggesting a well-differentiated neuroendocrine tumor. Based on the PET findings, the patient underwent distal pancreatectomy. Surgical pathology revealed only focal chronic pancreatitis with islet aggregation, a previously undescribed mimic of neuroendocrine tumor on DOTATATE PET/CT.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.