癌症中的 B 细胞异质性已经成熟。
B cell heterogeneity in cancer comes of age.
发表日期:2024 Oct 14
作者:
Colleen Sturdevant, Yuliya Pylayeva-Gupta
来源:
CANCER CELL
摘要:
B 细胞在癌症中的作用仍不完全清楚。最近发表的三篇出版物,包括 Fitzsimons 等人的一项研究。在本期《Cancer Cell》中,1 使用单细胞 RNA 测序来定义肿瘤浸润 B 细胞亚群的泛癌图谱,为我们深入了解 B 细胞依赖性抗肿瘤免疫铺平了道路。版权所有 © 2024 Elsevier Inc 。 版权所有。
The role of B cells in cancer remains incompletely understood. Three recent publications, including a study by Fitzsimons et al. in this issue of Cancer Cell,1 use single-cell RNA sequencing to define pan-cancer atlases of tumor-infiltrating B cell subsets, paving the way for profound advances in our understanding of B cell-dependent antitumor immunity.Copyright © 2024 Elsevier Inc. All rights reserved.