乳腺原发性腺泡细胞癌 (PACC) 是一种罕见的肿瘤实体，其模仿腺泡细胞分化，类似于在唾液腺中观察到的分化。这种独特的亚型的特点是低度恶性，并且仅在有限数量的病例中被记录。尽管乳腺 PACC 通常被分类为 TNBC，但通常表现出相对良好的预后。我们的研究旨在通过对我们机构管理的病例进行全面回顾，分析其临床、组织病理学和治疗概况（包括化疗和放疗）以及患者结果，丰富目前对 PACC 的了解，并使我们能够编制一个全面的数据集，用于：对治疗反应和长期生存率的深入分析，有助于更广泛地了解该疾病的自然史。版权所有 © 2024 作者。由爱思唯尔有限公司出版。保留所有权利。

Primary acinic cell carcinoma (PACC) of the breast is a rare oncological entity that mimics acinar cell differentiation similar to that observed in salivary glands. This distinct subtype is characterized by low-grade malignancy and has only been documented in a limited number of cases. Despite its classification frequently as TNBC, PACC of the breast typically shows a comparatively favorable prognosis. Our study aims to enrich the current understanding of PACC through a comprehensive review of cases managed at our institution, analyzing their clinical, histopathological, and therapeutic profiles including chemotherapy and radiation therapy, and patient outcomes and allows us to compile a comprehensive dataset for in-depth analysis of treatment responses and long-term survival rates, contributing to a broader understanding of the disease's natural history.Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.