研究动态
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增强健康和治疗潜力:大豆生物活性化合物的药用和制药特性的创新。

Enhancing health and therapeutic potential: innovations in the medicinal and pharmaceutical properties of soy bioactive compounds.

发表日期:2024
作者: Ubaidur Rahman, Zohaib Younas, Ilyas Ahmad, Tayyaba Yousaf, Rafia Latif, Ume Rubab, Hira Hassan, Unsa Shafi, Zia-Ur-Rehman Mashwani
来源: Frontiers in Pharmacology

摘要:

这篇彻底的综述对大豆生物活性成分的医学用途进行了广泛的研究。它探讨了具有植物雌激素特性的异黄酮可能对健康的好处,例如金雀异黄酮,它可以降低患癌症的风险。该综述强调了酚类化合物、植酸、蛋白酶抑制剂、木酚素和皂苷以及其他生物活性成分的不同作用和可能的抗癌活性。它还讨论了大豆中的膳食纤维和低聚糖对肠道健康的益处,以及大豆蛋白对糖尿病、肥胖、癌症和心血管健康的影响。共轭亚油酸(CLA)具有抗癌和降低胆固醇的特性;还检查了它在促进代谢过程中的作用。该研究强调松醇作为一种血糖调节剂,有望控制胰岛素信号传导。在这篇综述中,我们的目的是通过检查最近发现的治疗和药理能力来确认大豆作为高功能健康食品的潜力,而不是改进之前报道的大豆营养优势的研究。版权所有 © 2024拉赫曼、尤纳斯、艾哈迈德、优素福、拉蒂夫、鲁巴布、哈桑、沙菲和马什瓦尼。
An extensive examination of the medical uses of soybean bioactive components is provided by this thorough review. It explores the possible health advantages of isoflavones with phytoestrogenic qualities, like genistein, which may lower the risk of cancer. The review highlights the different roles and possible anticancer activities of phenolic compounds, phytic acid, protease inhibitors, lignans, and saponins, among other bioactive components. It also addresses the benefits of dietary fiber and oligosaccharides derived from soybeans for intestinal health, as well as the impact of soy protein on diabetes, obesity, cancer, and cardiovascular health. Conjugated linoleic acid (CLA) has anticancer and cholesterol-lowering properties; its involvement in promoting metabolic processes is also examined. Pinitol is highlighted in the study as a blood sugar regulator with promise for controlling insulin signaling. In this review, we aim to affirm soybeans' potential as a high-functional, well-being food by examining their recently discovered therapeutic and pharmacological capabilities, rather than to improve upon the previous studies on the reported nutritional advantages of soybeans.Copyright © 2024 Rahman, Younas, Ahmad, Yousaf, Latif, Rubab, Hassan, Shafi and Mashwani.