我们的目的是估计中国头颈鳞状细胞癌 (HNSCC) 患者在接受第一次放射治疗之前基线临床显着痛苦的发生率，并评估预测痛苦的因素。 168 名患者被纳入以完成一组问卷包括应激温度计（DT）和医院焦虑和抑郁量表（HADS）。其中，131份问卷可供最终分析。使用 HADS 作为金标准验证 DT 的准确性，并采用受试者工作特征 (ROC) 曲线来确定 DT 的最佳截止分数。 62 名患者 (47%) 报告了痛苦。上周访问过的患者（p = 0.022）和从事医疗相关职业的患者（p = 0.017）遭受心理困扰的可能性较小。此外，宗教信仰与 DT 和 HADS-T 评分均呈负相关，表明有宗教信仰的患者报告高水平痛苦的可能性较小（比值比 (OR) DT ≥ 4 = 0.291，p = 0.039；OR对于 HADS-T ≥ 15 = 0.316，p = 0.047）。年龄、性别、婚姻状况、教育程度和居住地等因素不会影响痛苦程度。 DT 与 HADS-T 显着相关（相关系数 (r) = 0.624，p < 0.001），并且 DT 在筛查困扰时的最佳截止分数为 4。DT 是筛查 HNSCC 患者困扰的简单而有效的工具。© 2024 . 作者。

We aim to estimate the prevalence of baseline clinically significant distress in Chinese patients with head and neck squamous cell carcinoma (HNSCC) before receiving the first radiotherapy and assess factors predictive of distress.One hundred and sixty-eight patients were enrolled to complete a set of questionnaires including Distress Thermometer (DT) and Hospital Anxiety and Depression Scale (HADS). Of these, 131 questionnaires were available for the final analysis. The accuracy of DT was validated using HADS as the gold standard, and receiver operating characteristic (ROC) curves were employed to identify the optimal cutoff score of DT.Distress was reported in sixty-two patients (47%). Patients who were visited in the last week (p = 0.022) and those with medical-related occupations (p = 0.017) were less likely to suffer from psychological distress. Additionally, religious belief was negatively associated with both the DT and HADS-T scores, indicating that patients with religious beliefs were less likely to report high levels of distress (odds ratio (OR) for DT ≥ 4 = 0.291, p = 0.039; OR for HADS-T ≥ 15 = 0.316, p = 0.047). Factors such as age, gender, marital status, education and residency did not contribute to distress levels. DT was significantly correlated with HADS-T (Correlation coefficient (r) = 0.624, p < 0.001) and the best cutoff score of DT was 4 in screening distress.DT was a brief and effective tool to screen distress among HNSCC patients.© 2024. The Author(s).